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. 2021 Jul 21;12(1):4159–4173. doi: 10.1080/21655979.2021.1953822

Figure 2.

Figure 2.

Inhibiting circRNA_0082835 and/or EZH2 suppresses melanoma cell proliferation. (a-b) Relative expressions of circRNA_0082835 and EZH2 in different melanoma cell strains, detected by qPCR. *P < 0.05 and ***P < 0.001 vs. HM group. (c-d) Relative expressions of circRNA_0082835 and EZH2 in WM451 cells before and after transfection of shRNA-circ and/or shRNA-EZH2, detected by qPCR. (e) OD value of WM451 cells before and after transfection of shRNA-circ and/or shRNA-EZH2, detected by CCK-8. *P < 0.05, **P < 0.01 and ***P < 0.01 vs. Control group. #P < 0.05 and ###P < 0.001 vs. shRNA-NC group. $$$P < 0.001 vs. shRNA-circ group. &&&p < 0.001 vs. shRNA-EZH2 group