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AK006774 inhibits the I/R-induced oxidative stress and cardiac injury in vivo. (a) qPCR was used to evaluate the efficiency of AK006774-overexpressing adenovirus. (b) TTC staining was performed to evaluate the infarct area of the heart. (c) TUNEL staining was carried out to detect the apoptosis of cardiomyocytes. (d–f) The levels of LDH, MDA, and ROS in the myocardium were detected using commercial kits. ** p < 0.01 vs Ad-nc or sham group, # p < 0.05 vs I/R+ Ad-nc
