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Protein-protein interaction network and the most significant modules of differentially expressed genes. (a) The protein-protein interaction network was analyzed using the STRING database. There were 186 nodes and 2482 edges in the network. (b) The most significant module identified by the MCODE plugin (score ≥30) consists of 70 nodes and 2042 edges. (c) The cytoHubba plugin identified the top six genes as hub genes by the maximum correlation criteria method (score ≥5000)
