Table 1.
Significantly upregulated and downregulated pathways through gene set enrichment analysis
| Description | Enrichment score (ES) | Normalized enrichment score (NES) | P-value | False discovery rate (FDR) |
|---|---|---|---|---|
| Reactome_Transcriptional_Regulation_by_ Tumor Protein P53 | 0.600427 | 2.767542 | 0.001988 | 0.004122 |
| Reactome_Regulation_of_ Tumor Protein P53_Activity | 0.572310 | 2.066904 | 0.003816 | 0.006433 |
| Reactome_G2_M_DNA_Damage_Checkpoint | 0.570086 | 2.058872 | 0.005725 | 0.008753 |
| Reactome_Homologous_DNA_Pairing_and_ Strand_Exchange | 0.569061 | 1.972560 | 0.007692 | 0.010738 |
| Wp_G1_to_S_Cell_Cycle_Control | 0.555013 | 2.257859 | 0.001972 | 0.004122 |
| Reactome_G_Alpha_I_Signalling_Events | −0.566715 | −3.133801 | 0.002118 | 0.004122 |
| Reactome_Visual_Phototransduction | −0.727044 | −3.426219 | 0.002000 | 0.004122 |
| Reactome_The_Phototransduction_Cascade | −0.754767 | −3.314062 | 0.002008 | 0.004122 |
| Pid_Rhodopsin_Pathway | −0.780250 | −3.364626 | 0.002012 | 0.004122 |
| Reactome_Activation_of_The_Phototransduction_Cascade | −0.876170 | −3.201726 | 0.002092 | 0.004122 |