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. 2021 Sep 15;12(1):5679–5687. doi: 10.1080/21655979.2021.1967712

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Construction of circRNA–miRNA–mRNA network and expression of hsa_circ_0006766 during osteogenic differentiation of hBM-MSCs. (a) Relative expression of hsa_circ_0006766 during osteoblastic differentiation of hBM-MSCs as determined by qRT-PCR analysis. ns, not significant relative to D0 group, P > 0.05; * P < 0.05; ** P < 0.01. (b) The network of circRNA–miRNA–mRNA consisting of hsa_circ_0006766(green node), target miRNAs (yellow squares) and their target mRNAs(blue nodes), in which the bone metabolism related target mRNAs is marked with red