Figure 4.

Overexpression of miR-363 enhances the sensitivity of BC cells to TMX. Overexpression of miR-363 was further introduced in T47D-FOXD3-AS1 cells, while overexpression of TFF1 was introduced in 231-si-FOXD3-AS1 cells. A, the expression of miR-363 and TFF1 mRNA in cells was determined by RT-qPCR. B-E, cell viability and growth were detected by MTT (b-c), colony formation (d) and EdU labeling (e) assays. Repetition = 3. Data were exhibited as mean ± SD. In panels A, D and E, one-way ANOVA was used for data analysis, while data in panels B and C were analyzed using two-way ANOVA, and Tukey’s multiple comparison test was used for post hoc test after ANOVA. *, p < 0.05