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Targeting of PLD5 by miR-145-5p in PC cells
A: 3′UTR region of PLD5 containing the binding site for miR-145-5p in WT and MUT plasmids; B-C Luciferase activity of PLD5 WT or MUT 3′-UTR with miR-145-5p mimics or NC in LNCap (B) and PC-3 (C) cells; D-E: Expression of PLD5 mRNA in PCa specimens (D) and PCa cell lines (E); F-G Expression of PLD5 mRNA (F) and protein (G) in PCa cell lines after miR-145-5p mimics transfection. *P < 0.05 and **P < 0.01.
