Figure 1.

High-altitude hypoxia enhances the severity of ulcerative colitis in the DSS induced colitis mice model, 5 mice /group were used. (a) The effect of high-altitude hypoxia on the body weight during 8 days among groups (NC, normal group; ND, DSS group; HC, Hypobaric hypoxia group; HD, hypobaric hypoxia DSS group). (b) The effect of high-altitude hypoxia during 3 months among tested groups. (c) the results of disease active index among tested groups. (d, e) The length of colon among tested groups. *P < 0.05, **P < 0.01, ***P < 0.001