Figure 2.

circBCL11B silencing restricts cell progression and induced cell apoptosis A

Knockdown effect of siRNA oligos targeting circBCL11B in Cal-27 and SCC cells (p < 0.01). B-D Cell were transfected with siRNA targeting circBCL11B. CCK-8 cell proliferation assay (B), clonogenic assay (C), and EDU incorporation assay (D) demonstrated that knockdown circBCL11B inhibited cell proliferation in OSCC cells (p < 0.01). E The apoptosis level of different groups of CAL-27 and SCC9 cells (si-NC, si-circCBCL11b) was detected by flow cytometry (p < 0.01). Data are summary of three independent experiment.