Figure 8.
APCDD1L-AS1 knockdown enhances susceptibility to 5-FU in 5-FU-resistant OSCC cells by decreasing NSD2
(A) NSD2 expression was tested in cells transfected with Vector or oe-NSD2. (B-D) CCK-8, Colony formation assay and flow cytometry were employed to detect IC50, cell proliferation and apoptosis in HSC-3/5-FU and HN-4/5-FU cells transfected with sh-NC, sh-APCDD1L-AS1, or sh-APCDD1L-AS1+ oe-NSD2. *P< 0.05, **P < 0.01.