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. 2021 Aug 12;12(1):5085–5098. doi: 10.1080/21655979.2021.1955561

Figure 4.

Figure 4

A miR-4306 mimic upregulated endogeneous miR-4306 levels. ***p < 0.001 or **p < 0.01 compared with mimic NC. ##p < 0.01 compared with miR-4306 mimic-1

B-C Bioinformatics analysis and luciferase gene reporter assay showed that miR-4306 bound to the 3ʹUTR of LINC00958. D-E. Bioinformatics analysis and luciferase gene reporter assay showed that miR-4306 bound to the 3ʹUTR of AIM2. **p < 0.01 compared with WT-LINC00958 + mimic NC. F-G. RNA-binding protein immunoprecipitation (RIP) showed that Anti-SIRT1 antibody significantly enriched LINC00958 in immunoprecipitation. Data was shown as mean±SD. ***p < 0.001 compared with WT-AIM +mimic NC.