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A. LINC00958 and SIRT1 regulated mitochondrial-mediated apoptosis pathway. B LINC00958 regulated inflammasome-mediated pyroptosis-related proteins. C. LINC00958 and SIRT1 regulated autophagy-related proteins. D p53, SIRT1 and AIM2 levels were affected by LINC00958 and SIRT1. Data was shown as mean±SD. ***p < 0.001 or **p < 0.01 compared with LV-NC. ΔΔΔ p < 0.001, ΔΔp<0.01 or Δp<0.05 compared with LV-SIRT. ### p < 0.001, ## p < 0.01 or #p < 0.05 compared with LV-LINC00958
