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circRAB3IP knockdown inhibited OS cells proliferation, migration, and invasion. (a) circRAB3IP expression was decreased in U2OS and MG63 cells transfected with si-circRAB3IP. (b, c) The CCK-8 assay and colony formation assay were performed to determine the effects of circRAB3IP on cell proliferation of OS cells. (d, e) Transwell assay was used to detect the effects of circRAB3IP on cell migration and invasion of OS cells *P < 0.05
