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Rhein treatment affected PPARγ and INSR protein levels, and inflammation. The supernatant culturing Raw246.7 cells with LPS stimulation was collected and used to incubate with 3T3-L1 preadipocytes. (a). The expression of PPARγ and INSR. (b). The quantitative analysis of inflammatory factor IL-6, IL-1β and TNF-α. Each experiment was repeated at least three times. ***p < 0.001 versus control. #p < 0.05, ##p < 0.01, ###p < 0.001 versus Model
