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Rhein treatment increased p62 protein levels. Representative images of p62 immunoreactivity (green) in 3T3-L1 cells. The supernatant culturing Raw246.7 cells with LPS stimulation was collected and used to incubate with 3T3-L1 preadipocytes. This experiment was repeated four times. **p < 0.01, ***p < 0.001 versus control. #p < 0.05, ##p < 0.01, ###p < 0.001 versus Model
