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. 2021 Aug 19;12(1):5305–5322. doi: 10.1080/21655979.2021.1964889

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Downregulation of EGR1 reduces LC tumorigenesis in nude mice. a, volume of the xenograft tumors in nude mice (two-way ANOVA, *p < 0.05); b, weight of tumors on the 28^th d (two-way ANOVA, *p < 0.05); c, expression of in the tumor tissues detected by immunohistochemical staining (two-way ANOVA, *p < 0.05); d, formation of metastatic nodules in murine lung tissues assessed by HE staining (two-way ANOVA, *p < 0.05)