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. 2021 Aug 19;12(1):5305–5322. doi: 10.1080/21655979.2021.1964889

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — miR-675 and SESN3 affects viability and aggressiveness of LC cells. a, expression of miR-675 and SESN3 mRNA in HLE and Hep3B cells evaluated by RT-qPCR (two-way ANOVA, *p < 0.05); b, proliferation of HLE and Hep3B cells evaluated by colony formation assays (two-way ANOVA, *p < 0.05); c-d, migratory (c) and invasive (d) potentials of HLE and Hep3B cells evaluated by Transwell assays (two-way ANOVA, *p < 0.05); e, apoptosis of HLE and Hep3B cells evaluated by Hoechst 33,258 staining (two-way ANOVA, *p < 0.05); f, volume of the tumors in nude mice (two-way ANOVA, *p < 0.05); g, weight of the tumors on the 28^th d (two-way ANOVA, *p < 0.05)