Figure 4.

Circ_0008274 can promote the malignant behaviors of HCC cells by targeting miR-140-3p

(a).pcDNA-NC, pcDNA-circ_0008274 and pcDNA-circ_0008274+ miR-140-3p mimics were transfected into Huh-7 cells; and si-NC, si-circ_0008274-1 and si-circ_0008274-1+ miR-140-3p inhibitors were transfected into HepG2 cells. MiR-140-3p expression was detected by qRT-PCR.B & C The proliferation of Huh-7 or HepG2 cells were detected by CCK-8 and EdU experiments.D. Transwell assay was used to detect the migration and invasion of Huh-7 or HepG2 cells.* P < 0.05, ** P < 0.01, and *** P < 0.001.