Table 1.
Levels of biochemical markers in patients with colorectal cancer
| VARIABLES |
CONTROL (n = 53) |
PATIENTS (n = 91) |
P-VALUE (p = <0.05) |
|---|---|---|---|
| CREATININE (mg/L) | 0.78 ± 0.099 | 2.95 ± 0.25 | 0.011 |
| Hs-CRP (mg/L) | 0.92 ± 0.12 | 4.19 ± 0.58 | 0.038 |
| 8-OHdG (pg/ml) | 0.93 ± 0.29 | 21.26 ± 1.29 | 0.004 |
| TNF-α (pg/ml) | 24.29 ± 2.18 | 41.56 ± 2.47 | 0.031 |
| IsoP-2α (pg/ml) | 19.65 ± 3.19 | 102.25 ± 4.25 | 0.000 |
| MDA (nmol/ml) | 0.99 ± 0.14 | 7.89 ± 0.78 | 0.007 |
| COX-2 (ng/ml) | 0.74 ± 0.1 | 5.56 ± 0.65 | 0.024 |
| Total NFkB p65 (µg/ml) | 0.124 + 0.024 | 0.945 + 0.067 | 0.000 |
| SOD (IU/ml) | 1.16 ± 0.09 | 0.45 ± 0.041 | 0.009 |
| GSH (µmol/ml) | 7.89 ± 1.05 | 4.56 ± 0.68 | 0.006 |
| CAT (µmol/ml of Prot.) | 5.69 ± 0.51 | 3.15 ± 0.22 | 0.027 |
| NO (µmol/L) | 18.47 ± 2.17 | 47.59 ± 4.21 | 0.014 |
| MMP-9 (pg/ml) | 19.65 ± 5.02 | 84.26 ± 4.26 | 0.017 |
| MMP-11 (pg/ml) | 27.59 ± 2.21 | 51.26 ± 1.58 | 0.017 |
| MMP-2 (pg/ml) | 9.26 ± 1.44 | 19.58 ± 1.58 | 0.031 |
| MMP-19 (pg/ml) | 16.35 ± 2.31 | 46.35 ± 3.19 | 0.019 |
| VEGF-β (pg/ml) | 49.58 ± 2.62 | 99.35 ± 4.29 | 0.010 |
| Protein Carbonyl (µmol/ml) | 2.99 ± 0.38 | 9.68 ± 0.97 | 0.000 |
| TGF-β (pg/ml) | 8.26 ± 0.88 | 18.59 ± 1.53 | 0.021 |
| TAS (µmol/ml) | 21.59 ± 1.75 | 11.29 ± 0.99 | 0.000 |
| IL-6 (pg/ml) | 9.58 ± 1.12 | 28.26 ± 1.88 | 0.001 |
| IL-1 (pg/ml) | 6.35 ± 0.88 | 17.26 ± 1.77 | 0.011 |
| IL-4 (pg/ml) | 21.25 ± 1.99 | 32.18 ± 1.45 | 0.021 |
| IL-35 (pg/ml) | 0.174 ± 0.009 | 0.061 ± 0.007 | 0.031 |