Figure 4.

YEATS2 silence diminished migration and invasion ability in Detroit562 and FaDu cells. (a) Wound healing assay was conducted to detect the migration ability in Detroit562 and FaDu cells after YEATS2 siRNA transfection (at 100 × magnification). (b) Transwell assay was conducted to detect the invasion ability in Detroit562 and FaDu cells after YEATS2 siRNA transfection (at 200 × magnification). (c) Western blot was used to analyze active MMP-2 and active MMP-9 expression in Detroit562 and FaDu cells after YEATS2 siRNA transfection. Data were represented as mean ± SD at least three independent experiments and analyzed by one-way analysis of variance (ANOVA) followed by Tukey’s multiple comparison test. *p < 0.05 vs. the control siRNA group