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GPR39 reduced ox-LDL-induced macrophage apoptosis via inducing A20 expression. (a-b) The apoptosis of ox-LDL-treated macrophages in different treatment group, measured using TUNEL assay. (c-d) Relative protein expression of apoptosis-related Bcl-2, Bax, cleaved caspase3 and cleaved PARP in macrophages exposed to ox-LDL in different treatment group, detected by western blot assay. ***P < 0.001 vs. Control; ###P < 0.001 vs. ox-LDL; ΔP<0.05, ΔΔΔP<0.001 vs. ox-LDL+TC-G 1008 μM+siRNA-NC
