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WNT4 functioned as a downstream target of miR-637. (a) Binding sequences of miR-637 in WNT4 3ʹ UTR. (b) Luciferase reporter assay was employed to validate the targeting relationship between miR-637 and WNT4 (n = 3). (c) qRT-PCR and western blotting detection of WNT4 expression in endothelial cells transfected with miR-637 mimic/inhibitor or their negative controls (n = 3). (d) Interplay between miR-637 and WNT4 was estimated by the RNA pull-down assay (n = 3). **P < 0.01
