Figure 3.

Phloretin suppressed the yeast-to-hyphae transition of Candida albicans. C. albicans (1 × 10⁶ CFU/mL) was treated with 37.28, 74.55, or 149.10 μg/mL (the concentration equivalent to 0.5×, 1× or 2× MIC) phloretin. (a) Representative images of the hyphal formation of C. albicans. Scale bar = 200 μm. The hyphae inhibition rate (%) = (the number of hyphae_control – the number of hyphae_phloretin)/the number of hyphae_control×100%. (b-e) The relative expression of EAP1, ECE1, HWP1, and ALS3. *p < 0.05, **p < 0.01 versus Control