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Ibrutinib protected against cerebral I/R injury in diabetic mice dose-dependently. (a-b) The TTC staining and infarct size of brain tissue were shown, and (c) The H&E staining was performed for pathological changes (Scale bar: 100 μm). (d-e) Apoptotic cells were accessed by TUNEL assays and brown color indicates apoptotic cells (Scale bar: 50 μm). All results presented as mean SD, n = 6/group. *P < 0.05 vs. the DS group, #P < 0.05 vs. the DIR group
