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. 2021 Sep 14;12(1):6448–6458. doi: 10.1080/21655979.2021.1972198

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Overexpression of TREX1 activates the cGAS/STING pathway to induce apoptosis and decrease cell growth

(a): Western blot analysis representing expression of cGAS & STING after overexpression of TREX1 in SK-MEL-1 cell line. (b): Western blot analysis representing expression of cGAS & STING after overexpression of TREX1 in SK-HEP-1 cell line. (c): Western blot analysis representing involvement of TREX1 overexpression in regulating cGAS/STING pathway in SK-MEL-1 cell line. (d): Western blot analysis representing involvement of TREX1 overexpression in regulating pathways involved in apoptosis and cell growth in SK-MEL-1 cell line. (* = p > 0.05)