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. 2021 Oct 21;12(1):8100–8115. doi: 10.1080/21655979.2021.1985259

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — MiR-3064-5p attenuated cell proliferation and elevated cell apoptosis by inhibiting LEMD1

(a) Cell viability was detected in HCT116 and HCT8 cells transfected with NC, Si-LEMD1, miR-3064-5p inhibitor, and Si-LEMD1+ miR-3064-5p inhibitor. (b) Cell proliferation was detected in HCT116 and HCT8 cells transfected with NC, Si-LEMD1, miR-3064-5p inhibitor, and Si-LEMD1+ miR-3064-5p inhibitor. (c) Cell apoptosis was detected in HCT116 and HCT8 cells transfected with NC, Si-LEMD1, miR-3064-5p inhibitor, and Si-LEMD1+ miR-3064-5p inhibitor. *, P < 0.05; **, P < 0.001 compared with blank. ^#, P < 0.05; ^##, P < 0.001 compared with Si-LEMD1+ miR-3064-5p inhibitor. NC, negative control; Si-LEMD1, SiRNA-LEMD1; Si-LEMD1+ miR-3064-5p inhibitor, SiRNA-LEMD1+ miR-3064-5p inhibitor.