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. 2021 Sep 27;12(1):6923–6934. doi: 10.1080/21655979.2021.1974765

Figure 1.

Figure 1.

Multifaceted roles of CCL20 in breast cancer progression. CCL20 recruits dendritic cells and CCR6 Tregs to impair the function of T cells (a). CCL20 induces VEGF expression to foster angiogenesis (b). CCL20 activates Snail to upregulates mesenchymal markers and downregulates epithelial markers (c).CCL20 promotes the migration and invasion of cancer cells. CCL20 induces stem cell genes and ABCBI expression to enhance drug resistance (e)