Figure 2.

Circ0005654 suppresses the proliferation and aggressiveness of GC cells. A, circ0005654 expression after circ0005654 knockdown measured by RT-qPCR; B, OD values of cells after inhibition of circ0005654 assessed by CCK8; C, cell migration activity after inhibition of circ0005654 examined by Transwell assay; D, cell invasion activity after inhibition of circ0005654 examined by Transwell assay; E, cell apoptosis after inhibition of circ0005654 evaluated by Hoechst staining. Values are shown as the mean ± SD based on three independent experiments. *p < 0.05 vs cells transfected with NC. Experimental results were analyzed using two-way ANOVA followed by Tukey’s test