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. 2021 Jul 21;12(1):3886–3899. doi: 10.1080/21655979.2021.1940071

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Low expression of PAUPAR in CRC correlated with poor clinical indicators

(a) PAUPAR expression in human CRC tissues and paracancerous normal tissues was detected by qRT-PCR (n = 47). (b) The relationship between PAUPAR expression and T stage in CRC patients was analyzed. (c) The relationship between PAUPAR expression and lymph node metastasis in CRC patients was analyzed. (d) PAUPAR expression in normal colonic epithelial cells (CCD841 CoN cells) and six types of CRC cells (HCT116, HT29, LoVo, SW620, SW480, and HCT8) were determined by qRT-PCR. All the experiments were performed in triplicate. * P < 0.05, ** P < 0.01, *** P < 0.001.