Figure 1.

MiR-4537 regulates the proliferation and apoptosis of GC cells

(a) RT-qPCR showed the expression level of miR-4537 in GC tissues. (b) The expression level of miR-4537 in GC cell lines was shown in RT-qPCR. (c) FISH assay was performed to reveal miR-4537 in GC cell lines. (d) Overexpression efficiency of miR-4537 was detected by RT-qPCR. (e) Viability of HGC27 and KATO III cells was determined using CCK-8 assay. (f) The colony-formation ability of GC cells transfected with miR-4537 mimics or NC mimics was detected by colony formation assay. (g) The apoptosis of GC cells transfected with miR-4537 mimics or control vector was measured by flow cytometry. *p< 0.05, ** p < 0.01, *** p< 0.001.