Figure 3.

CPT1C overexpression attenuated oxidative stress in Aβ_25-35-induced HT22 cells. Following transfection of Ov-CPT1C or Ov-NC for 24 h, HT22 cells were treated with Aβ_25–35 for another 24 h

(a) ROS expression was detected using ROS kits. (b) MDA levels and SOD activity were measured using MDA and SOD kits, respectively. (c) The relative mRNA and protein expression of SOD1 and SOD2 in A_25-35-induced HT22 cells were measured using RT-qPCR and western blot, respectively. ***P < 0.001 vs. Control group, ^##P < 0.01 and ^###P < 0.001 vs A_25-35 + Ov-NC.