Table 2.
The expression of 4 DEmiRNAs in pathogenic environment from TCGA and GEO database
| miRNA | TCGA (colorectal cancer vs normal) |
GEO (with pathobionts VS without pathobionts) |
Role | |||
|---|---|---|---|---|---|---|
| LogFC | FDR | LogFC | P.value | Group Set | ||
| hsa-mir-223 | 3.057351 | 2.23E-07 | 1.398719 | 0.030564 | CR tissue + Fn VS control | Support |
| hsa-mir-32 | 3.841335 | 6.25E-22 | −1.490555 | 0.003800 | CRC tissue + Fn VS control | Oppose |
| hsa-mir-96 | 5.457990 | 5.53E-18 | 2.366778 | 0.009546 | CRC tissue + Fn VS control | Support |
| hsa-mir-106a | 4.314718 | 3.32E-07 | 1.2774166 | 0.020353 | CR tissue + Fn VS control | Support |
FDR, false discovery rate; FC, fold change; Role, the role of pathogenic on colorectal carcinogenesis and tumor progression; CR, Colorectum; Fn, Fusobacterium nucleatum