Figure 4.

MiR-218-5p was downregulated in OSCC tissues and cells and inversely correlated with HOXA-AS3 expression. (a) The expression of miR-218-5p in OSCC cell lines and NHOK was detected by qRT-PCR. (b) The expression of miR-218-5p in OSCC tissues and para-cancerous tissues was detected by qRT-PCR. (c) HOXA-AS3 and miR-218-5p expression level was negatively correlated in OSCC tissues (r = −0.759, P < 0.01, n = 38). (d) qRT-PCR was used to measure the expression level of miR-218-5p after HOXA-AS3 knockdown in OSCC cell lines. *P < 0.05, **P < 0.01