Skip to main content
. 2021 Aug 1;12(1):4747–4756. doi: 10.1080/21655979.2021.1952367

Figure 5.

Figure 5.

Downregulation of miR-2355-3p can inhibit the proliferative, migrative, and invasive capacity of LUAD cells, but ZCCHC14 can reverse this effect. (a) and (b) The results of miR-2355-3p and ZCCHC14 expression showed that the transfection was successful. (***P < 0.001). (c) and (d) Downregulated miR-2355-3p inhibits NCI-H1299 and Calu-3 cell proliferation, but si-ZCCHC14 abolished the suppressive effect. (***P < 0.001). (e) and (f) NCI-H1299 and Calu-3 cell migration were inhibited by knocking down miR-2355-3p expression but rescued by si-ZCCHC14. (***P < 0.001 ratio to anti-NC; ###P < 0.001 ratio to anti-miR+si-NC). (g) and (h) LUAD cell invasion was repressed by knocking down miR-2355-3p expression but recuperated by ZCCHC14 inhibitor. (**P < 0.01, ***P < 0.001 ratio to anti-NC; ##P < 0.01, ###P < 0.001 ratio to anti-miR+si-NC)