Figure 2.

Apoptosis in OA chondrocytes was significantly alleviated by icariin. (a). AO-PI staining was used to evaluate the apoptotic state of treated chondrocytes. Fluorescence intensity was decreased in the rapamycin and icariin groups and increased in the 3-methyladenine group. (b). Flow cytometry was used to determine the apoptotic rate of treated chondrocytes. Apoptotic rate was decreased in the rapamycin and icariin groups and increased in the 3-methyladenine group