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miR-425 negatively regulates DKK-3 expression by targeted combination. (a, b) The expression of miR-425 in GES-1, MGC-803 and SGC-7901 and cell lines after transfection. (c) Predicted binding sites between miR-425 and the 3ʹUTR sequence of DKK-3. (d, e) Relative luciferase activities of 3ʹUTR DKK-3 and 3ʹUTR mutant DKK-3. (f) Western blot analyses of p-P38, p-JNK, caspase-1, p-ASK1 in cells lines after transfection with miR-425 inhibitor (*p < 0.05 vs. NC inhibitor)
