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. 2021 Oct 25;12(1):8396–8406. doi: 10.1080/21655979.2021.1988376

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — PTP1B expression is highly elevated in malignant melanoma and correlates with poor survival

A. PTP1B mRNA expression analysis in MM, nevi and normal tissues (GSE3189; Normal, n = 7; Nevi, n = 18; Melanoma, n = 45).B. PTP1B mRNA expression analysis in primary and metastatic tissues (GSE8401; Primary, n = 31; Metastasis, n = 52).C. PTP1B mRNA expression analysis in normal, primary and metastatic tissues (GSE15605; Normal, n = 16; Primary, n = 46; Metastasis, n = 12)D. Overall survival of MM patients based on PTP1B mRNA expression (GSE19234; High, n = 23; Low, n = 21).E. PTP1B protein expression in nontumor and melanoma tissues by immunohistochemical AEC staining. Original magnification 400 × .F. PTP1B expression was analyzed in nontumor and melanoma tissues (Normal, n = 18; Melanoma, n = 82).