Figure 4.

miR-877-5p interacted with FOXM1. (a) The binding site between FOXM1 and miR-877-5p is shown. (b) The correlation between miRNA-143-3p and miR-877-5p expression in prostate cancer tissues was analyzed by Spearman correlation analysis. n = 101. (c) Expression of FOXM1 was measured using qRT-PCR in DU-145 cells that were transfected with mimic NC or miR-877-5p mimic separately; n = 5. (d) Luciferase activity was examined in DU-145 cell cotransfected with miR-877-5p mimic, mimic NC, miR-877-5p inhibitor, or inhibitor NC and WT-FOXM1 or MUT-FOXM1. n = 3. **P < 0.01, ***P < 0.001