Figure 6.

Butyrate inhibits intestinal inflammation in mice. (a) Mice were orally treated with C.rodentium (5 × 10⁸ CFU/mice) and treated with or without butyrate (200 mM) in drinking water for 10 days. Monitored mice weight every day. (b) Colonic histopathology was analyzed when mice were sacrificed on day 10. (c) Collected the feces and measured the CFU on day 4. (d) Mice were administrated with 2% DSS in drinking water for 7 days and switched to untreated water for another 3 days. Treated with or without butyrate (200 mM) in drinking water for 10 days, and mouse weights were monitored daily. (e) Histopathological change and histological score in of colon in mice colitis models. **p < 0.01. CFU, Colony forming unit; DSS, Dextran sulfate sodium