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Knockdown of GIT1 inhibited HNSCC tumor growth and metastasis in vivo. (a) Mice were killed and the tumors were isolated. (b) The tumor volumes were measured on the indicated days. (c) One month after cell injection, the average tumor weight was measured. (d) H&E staining showed the lung metastatic nodules. (e) The number of lung metastatic nodules in the mice GIT1 knockdown group was markedly reduced compared to the GIT1 control group. ∗p < 0.05, ∗∗p < 0.01.
