Table 2.
Overall Survival According to Subgroup
| Median (months) (95% CI) | 2-Year OS (%) (95% CI) | 3-Year OS (%) (95% CI) | |
|---|---|---|---|
| Newly diagnosed glioma (n = 317) | |||
| Resection rate ≥95% (n = 182) | 24.0 (20.3–32.2) | 50.2 (42.3–57.7) | 40.2 (32.4–47.9) |
| Resection rate <95% (n = 135) | 16.5 (14.0–20.8) | 36.9 (27.7–46.1) | 29.4 (20.6–38.7) |
| Age <65 years (n = 149) | 25.6 (20.8–NE) | 53.2 (44.6–61.1) | 44.8 (36.4–52.9) |
| Age ≥65 years (n = 168) | 16.5 (14.6–20.9) | 35.8 (27.4–44.3) | 25.0 (17.1–33.7) |
| WHO Grade III (n = 51) | NR (32.2–NE) | 72.8 (56.9–83.6) | 64.7 (48.1–77.2) |
| WHO Grade IV (n = 266) | 18.0 (16.0–21.7) | 39.4(33.0–45.8) | 30.2 (24.1–36.5) |
| Recurrent glioma (n = 189) | |||
| Resection rate ≥95% (n = 115) | 17.9 (14.3–21.7) | 36.2 (27.0–45.5) | 28.8 (20.0–38.1) |
| Resection rate <95% (n = 73) | 10.9 (8.6–14.4) | 24.5 (14.7–35.7) | 17.2 (8.4–28.6) |
| Age <65 years (n = 136) | 15.9 (13.3–21.5) | 34.4 (26.2–42.7) | 27.0 (19.2–35.4) |
| Age ≥65 years (n = 53) | 13.2 (9.3–16.1) | 23.5 (11.6–37.9) | 16.8 (6.7–30.9) |
| WHO Grade III (n = 52) | 32.3 (21.5–NE) | 58.7 (43.4–71.2) | 45.0 (29.6–59.2) |
| WHO Grade IV (n = 137) | 13.4 (10.9–15.1) | 21.2 (14.3–29.0) | 16.5 (10.1–24.2) |
CI, confidence interval; NR, not reached; NE, not estimated; OS, overall survival; WHO, World Health Organization.