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. 2021 Dec 31;12(4):e3. doi: 10.5037/jomr.2021.12403

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Copyright © Kassapidou M, Stenport VF, Johansson CB, Östberg AK, Hammarström Johansson P, Hjalmarsson L. Published in the JOURNAL OF ORAL & MAXILLOFACIAL RESEARCH (http://www.ejomr.org), 31 December 2021.

This is an open-access article, first published in the JOURNAL OF ORAL & MAXILLOFACIAL RESEARCH, distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 UnportedLicense (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work and is properly cited. The copyright, license information and link to the original publication on (http://www.ejomr.org) must be included.

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The columns from the heat map represent the specimen material (and control) and the rows represent the cytokine expression profiles from exposed (and non-exposed) peripheral blood mononuclear cells after three days of incubation.

The colour codes symbolize the mean levels of cytokine release from supernatants obtained from 10 anonymous healthy donors: red = high; black = intermediate; green = low.

Co-Cr = cobalt-chromium; W280 = Wirobond 280^®; Rc = Remanium^® Star; Rm = Remanium^® Star MDII; Rlm = Remanium^® Star CL; Zz = Zirkonzahn^® Sintermetall; CpTi4 = commercially pure titanium grade 4; Ti-6Al-4V = titanium alloy grade 23.