Table 4:
Multivariate analysis of risk factors associated with mortality in PID with antibody deficiency
Variable | Odds ratio | 95% confidence interval | Z | P value |
---|---|---|---|---|
Age | 0.97 | 0.93–1.01 | 1.36 | 0.17 |
Male sex | 2.61 | 0.58–13.2 | 1.23 | 0.22 |
Pre SARS-CoV-2 infection lymphocyte count | 10.8 | 2.85–65.2 | 3.05 | 0.002 |
Prophylactic antibiotics | 2.68 | 0.59–14.8 | 1.23 | 0.22 |
Immune suppression | 0.18 | 0.009–1.55 | 1.4 | 0.16 |
Bronchiectasis | 2.54 | 0.54–12.9 | 1.17 | 0.24 |
GL-ILD | 0.54 | 0.02–6.12 | 0.45 | 0.65 |
Cardiovascular disease | 6.76 | 0.64–88.8 | 1.55 | 0.12 |
Rheumatological disease | 3.46 | 0.02–987 | 0.47 | 0.64 |
Chronic liver disease | 16.5 | 2.05–160 | 2.56 | 0.01 |
Diabetes mellitus | 20.6 | 1.64–465 | 2.13 | 0.03 |
Chronic kidney disease | 1.81 | 0.02–64.5 | 0.29 | 0.77 |
Autoimmune cytopenias | 0.07 | 0.004–0.61 | 2.18 | 0.03 |
Chronic gastrointestinal disease | 1.79 | 0.33–8.95 | 0.70 | 0.48 |
Haematological malignancy | 0.64 | 0.001–27.8 | 0.17 | 0.87 |
Splenomegaly | 0.37 | 0.02–5.08 | 0.72 | 0.47 |
Other organ specific autoimmunity | 5.84 | 0.39–80.9 | 1.31 | 0.19 |