Figure 4.
AUC data correlates with sRGES. Spearman correlations between sRGES (summarized reversal gene expression score) and AUC (areas under the concentration–response curve) data for the cancer groups. The correlation coefficient for (A) GBM is rho = 0.41 p = 4.42e-10, (B) CLA is rho = 0.4 p = 1.05e-9, (C) MES is rho = 0.36 p = 8.39e-8, (D) PRO is rho = 0.36 p = 4.63e-8. Data for AUC was retrieved from Cancer Therapeutic Response Portal (CTRP v2), and the median AUC value was used for AUC data available across multiple cell lines.