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. 2021 Nov 20;47(2):618–629. doi: 10.1007/s00261-021-03331-1

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© The Author(s) 2021, corrected publication 2021

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Fig. 3 — Schematic representation shows geographic HCC recurrence patterns (orange). Reproduced from reference 9 with permission from The Radiologic Society of North America (RSNA). Intrazonal tumor occurs within a treatment site. Extrazonal tumor describes recurrent tumor that is juxtaposed to, but outside of, the treatment site. Segmental tumor occurs within the same segment as a previously treated lesion, but with normal intervening liver tissue, and may represent either a satellite nodule or de novo HCC. Remote recurrence is a new nodule, in a segment separate from any treatment site. Intrazonal and extrazonal tumors are considered true recurrence (i.e. LR-TR Viable), while segmental and remote tumors are considered new tumors (i.e. LR-4 or LR-5 lesion)