Fig. 3.

Probability of experiencing eye (A), CSR (B), nail (C), PPES (D), and skin disorders (E). The upper and lower open circles represent the presence or absence of disorder across the range of phosphate concentrations. The dots depict the observed incidence for the terciles of phosphate concentrations and the corresponding vertical bars represent the 95% CI. The full blue line and the associated shaded area represent the model-based exposure efficacy relationship and its 95% CI. CSR central serous retinopathy; CI confidence interval; OR odds ratio; PPES palmar-plantar erythrodysesthesia syndrome