Table 2.

Number of café-au-lait macules (CALM) in infants (< 1 year) and older children without a known underlying disorder as determined in 3 different studies

	Alper et al. (1979)	Whitehouse (1966)	Burwell et al. (1982)
Age of children analysed	Newborn–1 year	1 Month–5 years	4–11 years
Total number of children	4641	365	542	Σ = 5548
Children with 1 CALM	88 (1.9%)	69 (18.9%)	146 (26.9%)	Σ = 303 (5.5%)
Children with 2 CALM	26 (0.6%)	15 (4.1%)	30 (5.5%)	Σ = 71 (1.3%)
Children with 1 or 2 CALM	114 (2.5%)	84 (23%)	176 (32%)	Σ = 374 (6.7%)
Children with ≥ 3 CALM	10 (0.2%)	1 (0.3%)	11 (2%)	Σ = 22 (0.4%)