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. 2022 Jan 19;11:780545. doi: 10.3389/fcimb.2021.780545

Table 3.

Susceptibility of C. albicans to antifungals in the absence and presence of individual and synergistic combinations of piperine and thymol.

Zone of inhibition in mm
Miconazole Itraconazole Ketoconazole Nystatin
Control 26 16 26 17
Piperine (µg/mL) 32 27 17 28 18
8 28 17 28 20
4 30 18 29 18
Thymol (µg/mL) 32 29 20 30 19
8 29 19 29 22
4 28 18 28 19
2 27 19 31 20
Piperine + thymol (µg/mL) 8+8 29 19 28 22
8+4 29 21 29 21
8+2 29 21 29 20
4+8 29 18 26 17