Table 3.
Susceptibility of C. albicans to antifungals in the absence and presence of individual and synergistic combinations of piperine and thymol.
| Zone of inhibition in mm | |||||
|---|---|---|---|---|---|
| Miconazole | Itraconazole | Ketoconazole | Nystatin | ||
| Control | 26 | 16 | 26 | 17 | |
| Piperine (µg/mL) | 32 | 27 | 17 | 28 | 18 |
| 8 | 28 | 17 | 28 | 20 | |
| 4 | 30 | 18 | 29 | 18 | |
| Thymol (µg/mL) | 32 | 29 | 20 | 30 | 19 |
| 8 | 29 | 19 | 29 | 22 | |
| 4 | 28 | 18 | 28 | 19 | |
| 2 | 27 | 19 | 31 | 20 | |
| Piperine + thymol (µg/mL) | 8+8 | 29 | 19 | 28 | 22 |
| 8+4 | 29 | 21 | 29 | 21 | |
| 8+2 | 29 | 21 | 29 | 20 | |
| 4+8 | 29 | 18 | 26 | 17 | |