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Titers of rVSV-GP in the organs of infected mice
| Group | Day after injection | Average rVSV-GP titers (two mice), PFU/20 μg of organ | |||||
|---|---|---|---|---|---|---|---|
| blood | brain | liver | kidney | spleen | intestine | ||
| Intact immunosuppressed mice | 1 | - | - | - | - | - | - |
| 2 | - | - | - | - | - | - | |
| Immunosuppressed mice infected with rVSV-GP | 1 | 4.44 × 105 | – | 6.67 × 104 | 4.14 × 104 | 3.65 × 104 | – |
| 2 | 1.7 × 107 | – | 1.27 × 105 | 2.44 × 104 | 3.44 × 104 | – | |
| Immunosuppressed mice receiving rVSV-GP+aEv6–Fc | 1 | - | - | - | - | - | - |
| 2 | - | - | - | - | - | - | |
