Table 2.
Risk factors for retinopathy of prematurity.
| BPD (range) |
Days of oxygen (range) |
Days of invasive ventilation (range) |
Early-onset sepsis (%) |
Late-onset sepsis (%) |
PIVH (%) |
PVL (%) |
Small for GA (%) |
NEC (%) |
Thrombocytopenia (<150.000/mml) (%) |
RBC transfusion (%) |
RBC transfusion first week (%) |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Initial cohort (n = 431) |
144 (33.4) |
10 (0–231) |
0 (0–121) |
182 (42.2) | 174 (43.4) | 148 (34.3) | 62 (14.4) | 86 (19.9) | 23 (5.3) |
181 (42.0) |
187 (43.4) |
95 (22.0) |
|
No ROP (n = 323; 74.9%) |
66 (20.4) |
6 (0–226) |
0 (0–86) |
113 (35.0) | 92 (28.5) | 90 (27.9) | 34 (10.5) | 61 (19.0) | 11 (3.4) |
116 (35.9) |
97 (30.0) |
34 (10.5) |
|
ROP (n = 108; 25.0%) |
77 (71.3) |
46 (0–231) |
11 (0–121) |
69 (63.9) | 82 (76.0) | 58 (53.7) | 28 (26.0) | 25 (23.1) | 12 (11.1) |
65 (60.1) |
90 (83.3) |
61 (56.5) |
|
Type 1 ROP (n = 25; 5.8%) |
22 (88.0) |
86 (8–231) |
34 (0–121) |
17 (68.0) | 17 (68.0) | 17 (68.0) |
9 (36.0) |
7 (28.0) |
2 (8.0) |
16 (64.0) |
20 (80.0) |
18 (72.0) |
| DIGIROP cohort (n = 257) | 134 (52.1) |
30 (0–231) |
3 (0–121) |
143 (55.6) | 140 (54.4) | 115 (44.7) | 51 (19.8) |
45 (17.5) |
16 (6.2) |
127 (49.4) |
161 (62.6) |
91 (35.4) |
|
No ROP (n = 156; 60.7%) |
57 (36.5) |
19 (0–226) |
1 (0–86) |
76 (48.7) | 62 (39.7) | 59 (37.8) | 23 (14.7) |
22 (14.1) |
6 (3.8) |
64 (41.0) |
73 (46.8) |
31 (19.8) |
|
ROP (n = 101; 39.3%) |
77 (76.2) |
49 (0–231) |
12 (0–121) |
67 (66.3) | 78 (77.2) | 56 (55.4) | 28 (27.7) |
23 22.7) |
10 (9.9) |
15 (14.8) |
88 (87.1) |
60 (59.4) |
|
Type 1 ROP (n = 23; 8.9%) |
21 (91.3) |
86 (15–231) |
34 (0–121) |
16 (69.6) | 15 (65.2) | 16 (69.6) |
9 (39.1) |
7 (30.4) |
2 (8.7) |
15 (65.2) |
19 (82.6) |
19 (82.6) |
|
Cohort excluded from algorithm (n = 174) |
11 (6.3) |
3 (0–102) |
0 (0–102) |
39 (22.4) | 34 (19.5) | 33 (18.9) |
11 (6.3) |
41 (23.5) |
7 (4.0) |
54 (31.0) |
26 (14.9) |
4 (2.3) |
|
No ROP (n = 167; 96.0%) |
9 5.3) |
3 (0–56) |
0 (0–16) |
37 (22.1) | 30 (17.9) | 31 (18.5) |
11 (6.5) |
39 (23.4) |
5 (3.0) |
52 (31.1) |
24 (14.4) |
3 (1.8) |
|
ROP (n = 7; 4.0%) |
2 (28.6) |
19 (1–102) |
0 (0–59) |
2 (28.6) | 4 (57.1% | 2 (28.6) |
0 (0.0) |
2 (28.6) | 2 (28.6) |
2 (28.6) |
2 (28.6) |
1 (14.3) |
|
Type 1 ROP (n = 2; 1.1%) |
1 (50.0) |
55 (8–102) |
30 (0–59) |
1 (50.0) |
2 (100.0) | 1 (50.0) |
0 (0.0) |
0 (0.0) |
0 (0.0) |
1 (50.0) |
1 (50.0) |
1 (50.0) |